Coloplast Alterna Пластина длительного ношения (Long wear), фланец 60мм

Количество: 1 упаковка

Пластина Alterna - LongWear (Алтерна Лонг Вэр) для длительного ношения двухкомпонентной системы.
Адгезив пластины Alterna Curagard (Курагард) обеспечивает надёжную длительную фиксацию пластины, защищает кожу от воздействия агрессивного кишечного отделяемого, обеспечивает безболезненное отклеивание пластины.

За счет того, что Клеевой слой Alterna термопластичен: под воздействием естественного тепла кожи он становится пластичным и заполняет все складки и неровности кожи, препятствуя протеканию кишечного отделяемого или мочи под пластину, не стягивает кожу и не мешает движениям тела. Так же адгезивная (клеевая) пластина утолщена у стомы и истончается к краям. Пластина имеет ребристый край, что придает ей дополнительную гибкость и позволяет следовать изгибам тела.
Механическое фланцевое соединение с замком-защелкой двухкомпонентных калоприемников и уроприемников Alterna позволяет установить мешок на пластине, не оказывая при этом давления на переднюю брюшную стенку, обеспечивает надежное и герметичное соединение стомного мешка и пластины. Кроме того, мешок можно повернуть в любое удобное положение, не снимая с фланца пластины.

На кольце есть ушки для дополнительного крепления мешка с помощью пояса. Применение пояса уменьшает нагрузку на пластину, тем самым продлевает срок её использования.

Вырезаемое отверстие адгезивной пластины : 10 – 55 мм.

кол-во в упаковке: 5 шт

ПРОДАЮТСЯ ТОЛЬКО УПАКОВКОЙ! стоимость указана за упаковку.

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Гость30.10.2025

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Гость29.10.2025

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Гость30.10.2025

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Гость27.10.2025

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Гость30.10.2025

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Гость01.11.2025

Typical dosages range from 200 to 1000 milligrams per week, and a few customers might take even greater quantities. However, such excessive doses can enhance the risk of unwanted side effects and usually are not really helpful for non-medical purposes. Traditionally doses were prescribed in accordance with the licence for the product as determined by the manufacturer and medicines regulator. They have been dreadful suggestions typically leaving a affected person to be supraphysiological and in a steroid abuser state in the course of the first few days. Though Anavar may be less cardiotoxic compared to most anabolic steroids, it nonetheless has the potential to induce hypertension (high blood pressure). Whereas SARMs don’t convert to estrogen as many anabolic steroids do, they'll and nearly at all times will result in suppression of your normal testosterone production. This can range from mild suppression to virtually a whole shutdown of the body’s exercise in producing testosterone. There’s little point in combining these two SERMs for post-cycle therapy; as an alternative, select one primarily based on the kind of steroid cycle you’ve accomplished. Use HCG for the two weeks between stopping your cycle and starting PCT. In that case, frontloading may not be for you, however it does present an extra possibility for those who favor to not undertake a kickstart utilizing an oral steroid. Frontloading Testosterone Enanthate can get your blood plasma ranges up to 500mg much faster. This includes taking a double dose of 1000mg on the primary day (or no matter will be double the quantity of your chosen regular dosage). The larger proportion of self-reported pimples might also replicate an occurrence of this side impact at other time limits during AAS use, which would have been missed by visible examination on the end of a cycle. Bioactivation into an estrogen can occur with AAS which would possibly be a substrate for the aromatase enzyme. This pathway is especially related for testosterone (yielding 17β-estradiol). Anabolic steroids are synthetic compounds designed to imitate the effects of pure testosterone, serving to customers improve muscle mass, strength, and total efficiency. These steroids work by enhancing protein synthesis and nitrogen retention within the physique, that are key drivers for muscle development during a steroid cycle. For newbies, understanding how anabolic steroids interact with the physique is crucial for planning an efficient cycle and attaining the specified results. SERMs negate the adverse feedback on the pituitary exerted by estrogens, and aromatase inhibitors impede the formation of these estrogens. Each classes of compounds indeed increase testosterone ranges in men with hypogonadism due to various causes. Anabolic steroids are illegally utilized by athletes at all levels in sports activities, similar to bodybuilding, weightlifting, baseball, football, biking, wrestling, and heaps of others, to enhance their efficiency. Optimizing your steroid cycle includes extra than just picking a compound and setting a dose. To obtain the very best positive aspects, it’s essential to make use of a data-driven strategy that takes into consideration the sort of steroid, dosage, frequency, and any mixtures you might be utilizing. Monitoring your blood levels and tracking how your body responds lets you make informed adjustments throughout your cycle. One of crucial ideas to know is the half-life of a steroid. The half-life refers again to the period of time it takes for half of the lively dose of a compound to be eliminated from the body. Our TRT calculator is built with the goal of offering you a straightforward, reliable, and correct technique of determining an appropriate beginning dosage for your testosterone replacement remedy. If you could have any questions or would actually like more information about testosterone alternative remedy preparations for you, please contact Balance My Hormones. Our specialists are here that will assist you achieve optimal hormone levels and improve your quality of life. Our fast and easy Free Testosterone Calculator calculates free and bioavailable testosterone levels utilizing your complete testosterone, albumin, and SHBG. The dosages listed are typical starting doses and may be adjusted by a healthcare provider based mostly on the patient’s response to treatment, testosterone levels, and unwanted effects. Regular monitoring of testosterone levels, symptoms, and unwanted effects is important throughout TRT to ensure the remedy is safe and efficient. To handle this facet effect, some AAS customers resort to ancillary medicine for therapy. Obviously, discontinuing AAS can be the preferred answer for just about each facet impact. This might be encouraged by affected person education on the potential risks and addressing psychological points that preserve AAS use, such as body dysmorphia and addiction. If the patient is nonetheless unwilling to stop, physicians might think about treatment to minimize back harm, as is customary in the method and treatment of, for instance, people who smoke and alcoholics. These embrace bone marrow stimulation in leukemia, aplastic anemia, kidney disease, growth failure, loss of appetite, and lack of muscle mass in malignancy and bought immunodeficiency syndrome. The beneficial cycle length is within the 6-<a href="https://pedselite.com/the-perfect-dbol-cycle-for-beginners-in-4-weeks-or-8-weeks-gr/41454/">Οδηγίες για την παρακολούθηση της υγείας σας σε 8 εβδομάδες</a> week range for finest results whereas minimizing virilization risk. If it’s your first Anavar cycle, six weeks at 5 to 10mg is a perfect introduction to this steroid. You can begin at 10mg for the first six weeks, then enhance the dose to 15-20mg for the final two weeks to ramp up your outcomes. Relying on how the steroids are used, this will vary from comparatively small changes to the event of extreme masculine traits. So, although it’s not frequent, some feminine athletes and bodybuilders do select to use steroids for performance-enhancing benefits.

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Гость06.11.2025

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Гость27.03.2025

Consideration rivals, Klean Athlete Klean Creatine is the most effective choose for you, based on Moriarty. As it turns out, the product name isn’t false marketing—the powder is genuinely pure sufficient to earn an NSF Licensed for Sport sticker, she says. Every five-gram scoop of this supp incorporates no extra elements however creatine. Thorne Creatine is an amino acid powder that may enhance your workout routine. Myprotein are one of the established UK supplement brands and their Creatine Monohydrate powder is a great possibility if you’re looking for a vegan-friendly, clear and clear supplement to add to your regimen. There are also numerous studies into the potential advantages of creatine in relation to supporting your coaching and gym objectives. For this reason, a creatine supplement is often a well-liked alternative amongst fitness center goers for use after their exercise periods. As properly as being bought on its own in tablet and powder kind, it’s additionally generally added to different forms of health club dietary supplements such as pre exercises and publish exercises. Beta-alanine (an amino acid) may improve the consequences of creatine supplementation, while caffeine could intrude with creatine's results. As a stable creatine, it stands out as a outcome of it helps improve muscle progress and helps you acquire energy. So, if you’re using creatine presently, it could be worthwhile to attempt the Kre Alkalyn EFX offers. Pharmanutri’s creatine supplements help enhance the dimensions of muscle tissue, as properly as your strength and momentum when understanding so you make the most effective out of your session. Neutral in taste with a tinge of saltiness, this creatine complement enhances your body’s capacity to perform intensive workouts. Whether you’re a bodybuilder, athlete, aged, or suffering from neurodegenerative illness, this creatine supplement helps volumize muscle mass and gives your body a pleasant tone and cut. It improves exercise efficiency simply as properly as its different counterparts. Phosphocreatine is a substance created by our skeletal muscular tissues that serves as a buffer to take care of an energy form created by the cells known as adenosine triphosphate (ATP). Creatine supplementation is a proven method to profit your thoughts and body, and to accelerate the timetable for making upgrades to each. Creatine is doubtless one of the hottest nutritional aids identified to reinforce athletic efficiency. It is a naturally occurring, non-protein amino acid compound found primarily in pink meat and seafood. However, despite the confirmed benefits of creatine monohydrate, experts and complement manufacturers typically declare that different creatine forms, such as hydrochloride, are higher. 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Гость28.04.2025

It works by decreasing irritation, slowing down an overactive immune system, or changing cortisol normally made in the physique. Cortisol is a hormone that performs an essential role in how the physique responds to stress, illness, and harm. Different medication might interact with methylprednisolone, including prescription and over-the-counter medicines, nutritional vitamins, and herbal products. Tell every of your health care suppliers about all medicines you use now and any drugs you start or stop using. An overdose of MethylPREDNISolone Dose Pack just isn't expected to produce life threatening symptoms. Anavar can produce some mild androgenic results in males, and hair loss could be certainly one of these issues for males who've a genetic predisposition to baldness. It can also be advantageous for users who're cutting and vulnerable to dropping strength as a end result of extended restriction of energy. In our expertise, ladies can typically experience superior leads to muscle mass in comparability with males on Anavar, even with a modest dose of 5–10 mg per day. If you're taking prednisolone for longer than 3 weeks, otherwise you've been prescribed a high dose of more than 40mg daily, your physician or pharmacist provides you with a blue steroid treatment card. Prednisone is a powerful anti-inflammatory drug used to deal with situations of irritation. It is necessary to all the time weigh the risks towards the advantages when taking this medicine. Anavar can be thought of the best oral steroid for both high-quality muscle gains AND muscle retention whereas weight-reduction plan. After injecting, remove the needle and apply strain to the injection web site with a sterile cotton ball or swab. When drawing the steroid from the vial, it’s essential to make use of a sterile syringe and needle. Make positive to verify the dosage you propose to inject and draw the appropriate amount of steroid into the syringe. Make positive to avoid touching the injection site after cleaning it. Teenagers who take anabolic steroids may grow less than usual too. They additionally would possibly elevate their danger of health problems later in life. The anabolic steroids used by athletes are sometimes forms of testosterone made in a lab. Nevertheless, we hypothesize reductions in fat mass to be the first factor in topics reducing BP. Oral testosterone (undecanoate) can additionally be secure for the liver, with it being absorbed by way of the intestinal lymphatic route, thus stopping hepatic strain. One examine gave 2,800 mg per week of testosterone undecanoate to male topics for 21 days (2); yet none of them skilled any hepatotoxic stress, regardless of such an exceedingly giant dose. It is certainly one of the least androgenic steroids, making it a high decide for these wanting muscle gains without extreme unwanted aspect effects. Human Development Hormone (HGH) is a product that is so frequent it’s not even used solely by athletes and bodybuilders. It is a prescribed treatment for these affected by low levels of Insulin-like Progress Issue 1 or IGF-1. 300 mg/week of testosterone (enanthate), when taken for 20 weeks, caused HDL ranges to drop by simply 13%. Secondly, testosterone doesn’t cross by way of the liver, thus failing to stimulate hepatic lipase, an enzyme that may skew levels of cholesterol within the wrong path. There are a couple of reasons why testosterone doesn’t negatively have an result on blood stress considerably. Firstly, it converts to estrogen, with the female hormone having a positive impact on blood lipids. Testosterone is an FDA-approved injectable steroid used to treat tens of millions of males all around the world who are poor in natural testosterone. Nonetheless, we've found certain steroids to be safer than others, which is why several AAS are permitted by the FDA in drugs (while others are not). Turinabol is one other 17-Alpha Alkylated Steroid, thus, it causes harm to the liver. Anavar’s greatest aspect impact is kidney harm (nephrotoxicity). Kidneys are very sensitive and, unlike the liver, they can't recover after injury. Anabolic steroids used appropriately and under the steerage of your doctor could be secure for use. Our info is predicated on the outcomes of good-quality studies. It is written by a group of well being care professionals, scientists and editors, and reviewed by external consultants. There isn't any typically accepted upper limit for the overall number of steroid injections. That will rely upon various components, including what situation is being treated. Some of those trenbolone cycles are extremely harsh, and we now have discovered them to be very damaging to the physique (at least within the quick term). Thus, our sufferers make the most of Nolvadex and Clomid after this stack to resurrect testosterone levels (without the addition of hCG). Winstrol doesn't have a excessive androgenic score; nevertheless, it does trigger notable androgenic effects in our expertise. The common rule when planning a cycle is that the higher the Anavar dose is, the shorter the cycle you should be doing. Some prefer to stay on the edge, while there are these of us who want to stability the benefits and dangers. I think I’ll go to eight weeks on Anavar if I’m taking not more than 50mg. Your supplier may use imaging (such as ultrasound or X-ray fluoroscopy) to help guide the delivery of the treatment. Welcome to Rhino Steroids blog, your go-to resource for every little thing related to steroids, efficiency enhancement, and bodybuilding. Though no anabolic steroid is 100 percent safe, some are categorized as essential medicines by main well being organizations. The most important organs to protect throughout a steroid cycle are the center and liver, and these three oral steroids are the least damaging in this regard. The most secure oral anabolic steroid in our testing is testosterone undecanoate. Nonetheless, Anavar and Primobolan are additionally very gentle compounds with few unwanted side effects. Inform your doctor when you take any other medicines, including herbal treatments and dietary supplements, earlier than beginning steroid tablets. Prednisone is a type of medication generally identified as a corticosteroid or steroid. It is used to deal with a broad range of conditions together with allergies, blood issues, skin ailments, infections, sure cancers and to prevent organ rejection after a transplant. Prednisone is mimicking our body’s pure hormone referred to as cortisol. Cortisol is naturally secreted by your body in a daily rhythm where right before dawn it’s actually excessive after which it goes slowly down throughout the day. References: Winstrol steroid Side effects (<a href="https://www.appleradish.org/lauraz28157372">www.appleradish.org</a>)

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Гость25.10.2025

The broad signals assigned to Hε and the protons of the piperidine ring reflect the dynamic nature of the Lys side chain. Upon prolonged incubation with the combination of proteolytic enzymes, perhaps undergoing autoproteolysis, these signals generally moved upfield and have become broader. KPV is out there in multiple formulations together with capsules which are appropriate for research on gastrointestinal and systemic anti-inflammatory effects. "In terms of the protection profiles of α-MSH and its tripeptides, very few knowledge are currently available due to lack of toxicity research. Nonetheless, the super-potent analog of α-MSH, [Nle4-D-Phe7]-MSH, when administrated intravenously at doses of up to zero.6 mg/kg, ends in occasional gastrointestinal upset and facial flushing without main detrimental effects. Appears like KPV and BPC-157 are the 2 leaders in phrases of the use of peptides for enhancing general gut well being (likely through the decreased production of pro-inflammatory compounds). "…treatment with KPV led to earlier recovery and considerably stronger regain of physique weight. While alpha-MSH itself has numerous capabilities, KPV isolates the crucial anti-inflammatory exercise without the pigmentation effects. Its major mechanism of motion entails the inhibition of NF-κB (nuclear issue kappa-light-chain-enhancer of activated B cells), a grasp regulator of inflammatory responses inside cells. By dampening the signaling cascades that result in irritation, KPV peptide effectively helps to calm extreme immune responses. Support for Barrier RepairKPV peptide helps rebuild disrupted epithelial junctions and supports natural antimicrobial defenses, potentially helping skin recover extra readily after harm. In conclusion, the promising results from present studies underscore the need for continued analysis on KPV and its applications, paving the finest way for model spanking new, efficient remedies for inflammatory illnesses. Further experiments explored the affect of nitric oxide utilizing the inhibitor Nω-nitro-l-arginine methyl ester (l-NAME), which appeared to impede the accelerated therapeutic effect of KPV on corneal epithelial wounds. This means that the positive impression of KPV on corneal epithelial wound healing could also be linked to nitric oxide dynamics within the tissue. The development of sophisticated delivery methods and combination therapies has additional enhanced the compound’s therapeutic potential, with novel formulations demonstrating improved bioavailability and tissue-specific targeting. These advances place KPV peptide analysis at the forefront of next-generation anti-inflammatory therapeutic development. In conclusion, the promising outcomes from present studies underscore the need for continued analysis on KPV and its applications, paving the way for model new, efficient therapies for inflammatory illnesses. Peptides like CJC-1295 and Ipamorelin higher help fat burning by stimulating growth hormone release. Typical doses range from a hundred to 500 micrograms day by day, however healthcare suppliers ought to determine optimum quantities and methods. Whether Or Not alone or mixed with other treatments, KPV’s versatile administration suits these enhancing well being by way of peptide remedy. The cells completely broke apart—proof that the peptide works by destroying the bacterial membrane. This protein moves into the cell’s heart (the nucleus) and tells it to start out making more inflammation signals like IL-8 and eotaxin. These chemical substances name extra immune cells to the realm, which makes the inflammation worse. This article explains how KPV Peptide may tackle conditions corresponding to inflammation, leaky intestine syndrome, and digestive disorders like IBD. At NINGBO INNO PHARMCHEM CO.,LTD., we perceive the important significance of sourcing high-quality elements. We present KPV peptide that adheres to stringent purity standards, ensuring its effectiveness for research and improvement functions. By offering reliable access to this potent peptide, we empower innovators to create advanced well being solutions. KPV-mediated decrease of NF-κB activity was additionally confirmed by EMSA (Supplementary outcomes, Determine 1). KPV peptide is primarily used to reduce irritation, improve intestine well being, and promote wound healing. Ongoing analysis is investigating how KPV peptide may be applied to a broader vary of situations. Early indications counsel that it might be useful in treating neurodegenerative illnesses, continual pain, and even sure forms of cancer as a outcome of its anti-inflammatory and immune-modulating properties. The impact of KPV on cell cycle exercise was measured by bromodeoxyuridine (BrdU) incorporation into S-phase cells. KPV did not alter the proportion of cells in S-phase, however, it reversed the inhibition of cell development attributable to TNFα (Figure 2A). This was accompanied by activation of mTORC1, a department point regulator of transcription and translation (Figure 2B). Cells had been grown in 16-well coverslips for 3h in serum free medium containing 0-10μg.ml-1 KPV with or with out TNFα (5ng.ml-1). At the 3h time point, the medium was replaced with similar medium containing 10μM 5-bromo-2’-deoxyuridine (BrdU). The benefits lengthen far beyond cosmetic adjustments to incorporate faster injury recovery, lowered irritation, and better total therapeutic capability. The availability of detailed Kpv peptide COA and HPLC information offers essential validation for these mechanisms. Researchers can rely on the desired purity and composition to precisely assess the peptide's effects, whether or not in vitro research or as part of complex formulation improvement. This commitment to high quality solidifies our place as a premier excessive purity Kpv peptide provider. Explore how KPV peptide modulates the immune system to fight persistent inflammation. This broad anti-inflammatory spectrum additional differentiates KPV peptide and helps the call for prolonged research into its signaling mechanisms, optimal dosing methods, and selectivity versus other host molecules. Since our in vitro research showed that PepT1 has a very high affinity for KPV, it is rather probably that KPV is transported into infected colonic cells even if it is present at decrease concentrations. It is therefore affordable to hypothesize that orally administrated KPV is taken up by small intestine and inflamed colonic cells expressing PepT1, thereafter inhibiting epithelial inflammatory responses, together with cytokine secretion. The inhibition of chemoattractants expression by colonic epithelial cells reduces the transport of neutrophils through the underlying matrix, as well as throughout the epithelium. Thus, melanocortin receptors are attractive therapeutic targets in inflammatory, metabolic and cancerous illness states [1]. One of KPV’s main features is inhibiting NF-κB activation, a key regulator of pro-inflammatory cytokine production (Starowicz & Przewłocka). By decreasing levels of TNF-α, IL-6, and IL-1β, KPV might assist mitigate continual inflammation and support tissue restoration. References: <a href="https://www.soundofrecovery.org/derickmayne26">www.soundofrecovery.org</a>

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Coloplast Alterna Пластина длительного ношения (Long wear), фланец 60мм

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